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Lung-Targeted Transgene Expression of Nanocomplexed Ad5 Enhances Immune Response in the Presence of Preexisting Article

Yilong Yang, Shipo Wu, Yudong Wang, Fangze Shao, Peng Lv, Ruihua Li, Xiaofan Zhao, Jun Zhang, Xiaopeng Zhang, Jianmin Li, Lihua Hou, Junjie Xu, Wei Chen

Engineering 2023, Volume 27, Issue 8,   Pages 127-139 doi: 10.1016/j.eng.2022.12.007

Abstract:

Recombinant adenovirus serotype 5 (Ad5) vector has been widely applied in vaccine development targetingHowever, the high prevalence of preexisting anti-vector immunity compromises the immunogenicity of Ad5-charged human serum albumin nanoparticles ((+)HSAnp), which are capable of forming a complex with Ad5,significantly increase the transgene expression of Ad5 in both coxsackievirus-adenovirus receptor-positiveImportantly, in the presence of preexisting anti-Ad5 immunity, complexed Ad5-based Ebola and COVID-19

Keywords： Adenovirus serotype 5     Vaccine     Preexisting immunity     Nanoparticles     Transgene expression    

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Serologic study on the outbreak of acute upper respiratory tract infections caused by adenovirus 3

JIANG Lufang, JU Liwen, LIN Yuzun, ZHOU Liandi, YU Shunzhang, JIANG Qingwu, JIANG Renjie

Frontiers of Medicine 2007, Volume 1, Issue 2,   Pages 215-218 doi: 10.1007/s11684-007-0041-3

Abstract: Twenty throat swabs were collected with 13 of them presenting an adenovirus (Ad)-like cytopathogenicMoreover, they were identified as adenovirus type 3 (Ad3) by type-specific PCR and sequencing of thestudy, we can definitively diagnose that this outbreak of acute respiratory infections was caused by Adenovirus

Keywords： Twenty     Adenovirus     cytopathogenic     type-specific     AURTI    

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5G Falls Short of Promised Benefits

Mitch Leslie

Engineering 2023, Volume 29, Issue 10,   Pages 5-7 doi: 10.1016/j.eng.2023.08.003

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Application of 5G Technology in Education Informatization

Lu Xiangqun, Sun Yu

Strategic Study of CAE 2019, Volume 21, Issue 6,   Pages 120-128 doi: 10.15302/J-SSCAE-2019.06.020

Abstract: The fifth generation mobile communication (5G) technology, with its characteristics of large bandwidthThis paper focuses on the application of 5G technology in education informatization.analyzes the technical challenges faced by the education network of China, and demonstrates corresponding 5Gresearch, and education management, thereby forming an overall view of education informatization based on 5GBy 2035, the 5G technology will be further promoted, which will constantly enrich the connotation and

Keywords： education     information technology     education informatization     5G technology     application scenarios    

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Decoupling methods of MIMO antenna arrays for 5G applications: a review Review Articles

Xiao-xi ZHANG, Ai-di REN, Ying LIU

Frontiers of Information Technology & Electronic Engineering 2020, Volume 21, Issue 1,   Pages 62-71 doi: 10.1631/FITEE.1900466

Abstract: For future fifth-generation (5G) terminals, it is still a challenging task to realize desirable isolationorthogonal modes, and reduction of ground effect, and discuss the development trends of the MIMO array in 5G

Keywords： MIMO array     5G smartphone     Decoupling methods    

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Investigation of gene therapy of denovirus in immune suppression

XIA Xi, WANG Beibei, CAO Li, CHEN Gang, WU Peng, LU Yunping, ZHOU Jianfeng, MA Ding

Frontiers of Medicine 2008, Volume 2, Issue 4,   Pages 386-390 doi: 10.1007/s11684-008-0074-2

Abstract: The aim of this paper is to investigate the safety of reconstructed adenovirus in immunosuppressive therapeuticsImmunohistochemistry was used to examine the expression of adenovirus in organs.as time went by in the control group, while it did not happen in the experimental group in which the adenovirusshowed a relative increase compared with their counterparts ( < 0.05). (3) The distributions of adenovirusReconstructed adenovirus as a vector is definitely safe in immunosuppressive therapeutics, and ciclosporin

Keywords： different     reversible inflammation     immunohistochemistry     reconstructed adenovirus     ciclosporin    

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lncR-GAS5 upregulates the splicing factor to impair endothelial autophagy, leading to atherogenesis

Frontiers of Medicine 2023, Volume 17, Issue 2,   Pages 317-329 doi: 10.1007/s11684-022-0931-4

Abstract: Here, we investigated the role of the lncRNA growth arrest-specific 5 (lncR-GAS5) in atherogenesis.By contrast, lncR-GAS5 knockdown promoted autophagy.Further results revealed that overexpression of the lncR-GAS5-targeted gene miR-193-5p promoted autophagyNotably, miR-193-5p overexpression decreased plaque size and increased collagen content.In conclusion, lncR-GAS5 overexpression arrested endothelial autophagy through the miR-193-5p/SRSF10

Keywords： lncR-GAS5     miR-193-5p     splicing factor SRSF10     autophagy     atherogenesis    

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2020普遍通信与5G技术国际会议(UC5G 2020)

Conference Date: 26 Mar 2020

Conference Place: 上海

Administered by: APISE

Boehmite-supported CuO as a catalyst for catalytic transfer hydrogenation of 5-hydroxymethylfurfural

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 4,   Pages 415-424 doi: 10.1007/s11705-022-2225-4

Abstract: Herein, we prepared a boehmite-supported copper-oxide catalyst for the selective hydrogenation of 5-hydroxymethylfurfural

Keywords： biomass     5-hydroxymethylfurfural     2     5-bis(hydroxymethyl)furan     transfer hydrogenation     catalysis    

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A Storm over Potential 5G Interference

Chris Palmer

Engineering 2019, Volume 5, Issue 5,   Pages 815-816 doi: 10.1016/j.eng.2019.08.007

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2020年5G移动通信与信息科学国际学术会议（MCIS-5G2020）

Conference Date: 26 Jun 2020

Conference Place: 广东广州

A tutorial on 5G and the progress in China None

Shan-zhi CHEN, Shao-li KANG

Frontiers of Information Technology & Electronic Engineering 2018, Volume 19, Issue 3,   Pages 309-321 doi: 10.1631/FITEE.1800070

Abstract: 5G has been developing at high speed since 2012 and has become a global economic driver., frequency management, technology trials, industrial ecology, and a list of main 5G contributors.We also point out the contributions to 5G from China, aiming to be ‘globally leading in 5G’ by actingas a main 5G contributor in standardization and promoting/enhancing the Chinese 5G industry.Finally, progress on 5G is reviewed mixed with our rethinking of 5G.

Keywords： 5G     IMT-2020     Key technology     Standardization     Field trial    

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Management innovation of Chang’e-5 project

Frontiers of Engineering Management 2021, Volume 8, Issue 4,   Pages 620-626 doi: 10.1007/s42524-021-0165-1

Keywords： lunar exploration     sample return     systems engineering     project management    

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Sodium butyrate activates HMGCS2 to promote ketone body production through SIRT5-mediated desuccinylation

Frontiers of Medicine 2023, Volume 17, Issue 2,   Pages 339-351 doi: 10.1007/s11684-022-0943-0

Abstract: The SB effect was significantly reduced by a SIRT5 inhibitor and in Sirt5-KO mice.The data suggests that SB activated HMGCS2 through SIRT5-mediated desuccinylation for ketone body production

Keywords： sodium butyrate     succinylation     HMGCS2     ketogenesis     SIRT5    

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Catalytic hydrogenation of insoluble organic matter of CS/Acetone from coal over mesoporous HZSM-5 supported

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 10,   Pages 1505-1513 doi: 10.1007/s11705-022-2164-0

Abstract: Four supported catalysts, nickel and ruthenium on a HZSM-5 support, were prepared by equal volume impregnationand extraction residue of Naomaohu lignite as the sample under an initial H2 pressure of 5According to the catalytic hydro-conversion results of the model compound, Ni−Ru/HZSM-5 exhibited theheterolytically split H···H into immobile H‒ attached on the acidic centers of Ni−Ru/HZSM-5extraction residue from Naomaohu lignite was further examined over the optimized catalyst, Ni−Ru/HZSM-5.

Keywords： HZSM-5     Ni-based catalyst     catalytic hydrogenation     coal     model compound    

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Title Author Date Type Operation

Lung-Targeted Transgene Expression of Nanocomplexed Ad5 Enhances Immune Response in the Presence of Preexisting

Yilong Yang, Shipo Wu, Yudong Wang, Fangze Shao, Peng Lv, Ruihua Li, Xiaofan Zhao, Jun Zhang, Xiaopeng Zhang, Jianmin Li, Lihua Hou, Junjie Xu, Wei Chen

Journal Article

Serologic study on the outbreak of acute upper respiratory tract infections caused by adenovirus 3

JIANG Lufang, JU Liwen, LIN Yuzun, ZHOU Liandi, YU Shunzhang, JIANG Qingwu, JIANG Renjie

Journal Article

5G Falls Short of Promised Benefits

Mitch Leslie

Journal Article

Application of 5G Technology in Education Informatization

Lu Xiangqun, Sun Yu

Journal Article

Decoupling methods of MIMO antenna arrays for 5G applications: a review

Xiao-xi ZHANG, Ai-di REN, Ying LIU

Journal Article

Investigation of gene therapy of denovirus in immune suppression

XIA Xi, WANG Beibei, CAO Li, CHEN Gang, WU Peng, LU Yunping, ZHOU Jianfeng, MA Ding

Journal Article

lncR-GAS5 upregulates the splicing factor to impair endothelial autophagy, leading to atherogenesis

Journal Article

2020普遍通信与5G技术国际会议(UC5G 2020)

26 Mar 2020

Conference Information

Boehmite-supported CuO as a catalyst for catalytic transfer hydrogenation of 5-hydroxymethylfurfural

Journal Article

A Storm over Potential 5G Interference

Chris Palmer

Journal Article

2020年5G移动通信与信息科学国际学术会议（MCIS-5G2020）

26 Jun 2020

Conference Information

A tutorial on 5G and the progress in China

Shan-zhi CHEN, Shao-li KANG

Journal Article

Management innovation of Chang’e-5 project

Journal Article

Sodium butyrate activates HMGCS2 to promote ketone body production through SIRT5-mediated desuccinylation

Journal Article

Catalytic hydrogenation of insoluble organic matter of CS/Acetone from coal over mesoporous HZSM-5 supported

Journal Article